• Applications—
  • Sensitive Active Ingredients & Containment Applications

Sensitive Active Ingredients & Containment Applications

Maximum Precision for Highly Sensitive Production Environments.

When processing highly potent or sensitive active ingredients, special requirements apply in terms of precision, dimensional accuracy and process reliability. Even the smallest deviations can have a direct impact on dosage, quality and safety.

NOTTER develops tooling systems designed for maximum manufacturing accuracy and reproducible results.

Requirements for Sensitive Active Ingredients

Applications involving highly potent or sensitive substances place special requirements on:

Tooling and Process:

  • Precise dosing accuracy
  • Minimal tolerances
  • Reproducible tablet properties
  • High requirements for cleanliness and surface quality

Typical Fields of Application:

  • Oncology preparations
  • Hormonal active ingredients
  • Highly potent APIs
  • Special pharmaceutical products

In these areas, reliable process control is the primary focus.

Precision Solutions by NOTTER

For sensitive applications, NOTTER relies on the highest manufacturing quality and coordinated design solutions. Through controlled manufacturing processes, tight tolerances and comprehensive quality inspection, NOTTER ensures that tools function reproducibly even under demanding conditions.

Dimensionally Accurate Tool Geometries

Precisely manufactured punch and die components ensure the exact transfer of the intended tablet geometry.

 

Learn more

Adapted Coatings

When tools need to be specifically optimized for a particular process, choosing the right surface coating can make a decisive difference in process reliability. 

 

Learn more

Adapted Materials

Hardness and toughness are important parameters in tableting tools. The head must be hard in order to minimize wear, while the tip needs to be tougher so that it does not break under load.

 

Learn more

Case study: Corrosion problems

After switching to the two new alloys, the tools were no longer corroded and GMP-compliant production was ensured.

  • Maximum corrosion resistance
  • GMP-compliant production

To the case studies

Want to know more about NOTTER solutions?

Contact our team of experts to discuss your individual requirements and receive a customized solution for your tablet production process.

We look forward to receiving your e-mail or phone call!

Anfrage (EN)

Formular

Harald Römer
Application consultant

 +49 (0) 160 / 97841847
 +49 (0) 7043 / 9258-39